Laboratoire Différenciation et Communication Neuroendocrine, Endocrine et Germinale
INSERM U1239

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PROFIL

Jerome LEPRINCE

ÉQUIPE : Peptides Régulateurs, Métabolisme énergétique et Comportements motivationnels

E-MAIL : jerome.leprince@univ-rouen.fr

STATUT : Chargé de recherche INSERM

ORCID : 0000-0002-7814-9927

Jérôme Leprince defended his PhD thesis in 2001 on the structure-activity relationships of the neuropeptide ODN and obtained his HDR in 2009. He joined INSERM in 1999 as a full-time engineer and became researcher in 2002. He is now Deputy- director of the laboratory of Neuroendocrine, Endocrine and Germinal Differentiation and Communication, INSERM U1239 NorDiC in Rouen. He is also heading the Peptide Synthesis and Functional Screening facilities of PRIMACEN Cellular Imaging Platform, INSERM US51 HeRacLeS.

Jérôme Leprince received a “Vocation Prize in Therapeutic Chemistry” in 1999 from the French Society of Therapeutic Chemistry for his contribution to the pharmacochemistry of the endozepinergic system. His current research focuses on the design and the development of peptide- based G protein-coupled receptor ligands for pharmacological, therapeutic and/or diagnostic interests in energy homeostasis.

DERNIÈRES PUBLICATIONS DE JEROME LEPRINCE

MRGPRB2/X2 and the analogous effects of its agonist and antagonist in DSS-induced colitis in mice

Publié en 2024 dans Biomedicine & Pharmacotherapy

Équipe : Peptides Régulateurs, Métabolisme énergétique et Comportements motivationnels

The 26RFa (QRFP)/GPR103 neuropeptidergic system: A key regulator of energy and glucose metabolism

Publié en 2024 dans Neuroendocrinology

Équipe : Peptides Régulateurs, Métabolisme énergétique et Comportements motivationnels

The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes

Publié en 2023 dans iScience

Équipe : Peptides Régulateurs, Métabolisme énergétique et Comportements motivationnels

Peptidomic analysis of the host-defense peptides in skin secretions of the Amazon River frog Lithobates palmipes (Ranidae)

Publié en 2023 dans Comparative Biochemistry and Physiology D-Genomics & Proteomics

Équipe : Peptides Régulateurs, Métabolisme énergétique et Comportements motivationnels

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